Deposited model

PDB 4R6V|dpdb_wy5m501l

Deposited model

Crystal Structure of FGF Receptor (FGFR) 4 Kinase Harboring the V550L Gate-Keeper Mutation in Complex with FIIN-3, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming FGFR kinase Gate-Keeper Mutations

Program
PHENIX 1.8.4_1496)
Model type
Deposited
Purpose
Reference
Authors
Huang, Z., Mohammadi, M.
Atoms
2,227
Residues
273
Protein chains
1
Unmodeled fraction
15.48%
Ligand
FI3

Evaluations

R-work
0.174
R-free
0.227
Clashscore
5.5

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Fibroblast growth factor receptor 4323
  • ConstructTyrosine Kinase Domain of FGF receptor 4
  • MutationsR664E V550L

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations